{"id":2338,"date":"2024-05-27T21:01:09","date_gmt":"2024-05-27T12:01:09","guid":{"rendered":"https:\/\/www.soyokazesogo.com\/blog\/?p=2338"},"modified":"2024-05-24T21:15:10","modified_gmt":"2024-05-24T12:15:10","slug":"gs-441524%e3%81%ae%e6%b2%bb%e7%99%82%e3%81%a8%e8%ab%96%e6%96%87","status":"publish","type":"post","link":"https:\/\/www.soyokazesogo.com\/blog\/gs-441524%e3%81%ae%e6%b2%bb%e7%99%82%e3%81%a8%e8%ab%96%e6%96%87\/","title":{"rendered":"GS-441524\u306e\u6cbb\u7642\u3068\u8ad6\u6587"},"content":{"rendered":"<div class=\"py-2 juice:py-[18px] px-3 text-base md:px-4 m-auto md:px-5 lg:px-1 xl:px-5\">\n<div class=\"mx-auto flex flex-1 gap-3 text-base juice:gap-4 juice:md:gap-6 md:max-w-3xl lg:max-w-[40rem] xl:max-w-[48rem]\">\n<div class=\"group\/conversation-turn relative flex w-full min-w-0 flex-col agent-turn\">\n<div class=\"flex-col gap-1 md:gap-3\">\n<div class=\"flex flex-grow flex-col max-w-full\">\n<div class=\"min-h-[20px] text-message flex flex-col items-start whitespace-pre-wrap break-words [.text-message+&amp;]:mt-5 juice:w-full juice:items-end overflow-x-auto gap-2\" dir=\"auto\" data-message-author-role=\"assistant\" data-message-id=\"f69dc408-b19f-499c-b1f6-ceedccdbe5c6\">\n<div class=\"flex w-full flex-col gap-1 juice:empty:hidden juice:first:pt-[3px]\">\n<div class=\"markdown prose w-full break-words dark:prose-invert light\">\n<h1>GS-441524\u306e\u6cbb\u7642\u306b\u3064\u3044\u3066\u306e\u8ad6\u6587<\/h1>\n<p>GS-441524\u306f\u3001\u732b\u4f1d\u67d3\u6027\u8179\u819c\u708e\uff08FIP\uff09\u306b\u5bfe\u3059\u308b\u52b9\u679c\u7684\u306a\u6cbb\u7642\u6cd5\u3068\u3057\u3066\u5e83\u304f\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u7814\u7a76\u8ad6\u6587\u3082\u8907\u6570\u5b58\u5728\u3057\u3001\u305d\u306e\u6cbb\u7642\u52b9\u679c\u3084\u30e1\u30ab\u30cb\u30ba\u30e0\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u63a2\u6c42\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4ee5\u4e0b\u306f\u3001\u3044\u304f\u3064\u304b\u306e\u4e3b\u8981\u306a\u7814\u7a76\u3068\u305d\u306e\u5185\u5bb9\u3067\u3059\u3002<\/p>\n<h2 style=\"text-align: left;\"><strong>\u6297\u30a6\u30a4\u30eb\u30b9\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u89e3\u660e<\/strong><\/h2>\n<p style=\"text-align: left;\">Cornell\u5927\u5b66\u306e\u7814\u7a76\u3067\u306f\u3001GS-441524\u306e\u6297\u30a6\u30a4\u30eb\u30b9\u30e1\u30ab\u30cb\u30ba\u30e0\u304c\u8a73\u7d30\u306b\u691c\u8a0e\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u7814\u7a76\u306f\u3001GS-441524\u304c\u30a6\u30a4\u30eb\u30b9RNA\u306e\u5408\u6210\u3092\u963b\u5bb3\u3059\u308b\u6838\u9178\u985e\u4f3c\u4f53\u3068\u3057\u3066\u6a5f\u80fd\u3059\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u30a6\u30a4\u30eb\u30b9\u30de\u30af\u30ed\u30c9\u30e1\u30a4\u30f3\u306b\u3082\u7d50\u5408\u3057\u3001\u5bbf\u4e3b\u306e\u6297\u30a6\u30a4\u30eb\u30b9\u9632\u5fa1\u30b7\u30b9\u30c6\u30e0\u3092\u5f37\u5316\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u3092\u793a\u5506\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u4e8c\u91cd\u306e\u4f5c\u7528\u30e1\u30ab\u30cb\u30ba\u30e0\u306f\u3001GS-441524\u306e\u9ad8\u3044\u52b9\u679c\u3092\u8aac\u660e\u3059\u308b\u91cd\u8981\u306a\u8981\u7d20\u3067\u3059\u200b<span class=\"\" data-state=\"closed\"><span class=\"text-token-text-secondary\"> (<\/span><a class=\"text-green-600 !no-underline\" href=\"https:\/\/www.vet.cornell.edu\/research\/awards\/202312\/elucidating-antiviral-mechanism-gs-441524-and-developing-novel-therapeutic-targets-feline-infectious\" target=\"_blank\" rel=\"noopener noreferrer\">Cornell Vet<\/a><span class=\"text-token-text-secondary\">)<\/span><\/span>\u200b\u3002<\/p>\n<h2><strong>\u6cbb\u7642\u6210\u529f\u7387\u3068\u7d4c\u53e3\u6295\u4e0e<\/strong><\/h2>\n<p>\u6700\u8fd1\u306e\u7814\u7a76\u3067\u306f\u3001GS-441524\u306e\u7d4c\u53e3\u6295\u4e0e\u3068\u6ce8\u5c04\u6295\u4e0e\u306e\u6bd4\u8f03\u3082\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u7d4c\u53e3\u6295\u4e0e\u306f\u732b\u306e\u30b9\u30c8\u30ec\u30b9\u3092\u8efd\u6e1b\u3057\u3001\u98fc\u3044\u4e3b\u306b\u3082\u6271\u3044\u3084\u3059\u3044\u65b9\u6cd5\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305f\u3060\u3057\u3001\u7d4c\u53e3\u6295\u4e0e\u3067\u306f\u5438\u53ce\u7387\u304c\u4f4e\u4e0b\u3059\u308b\u5834\u5408\u304c\u3042\u308a\u3001\u7279\u306b\u6d88\u5316\u5668\u7cfb\u306b\u554f\u984c\u3092\u62b1\u3048\u308b\u732b\u306b\u306f\u4e0d\u9069\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u6ce8\u5c04\u6295\u4e0e\u3068\u7d4c\u53e3\u6295\u4e0e\u306e\u6210\u529f\u7387\u306f\u307b\u307c\u540c\u7b49\u3067\u3042\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u4e00\u90e8\u306e\u732b\u3067\u306f\u7d4c\u53e3\u6295\u4e0e\u306b\u5bfe\u3059\u308b\u53cd\u5fdc\u304c\u6ce8\u5c04\u6295\u4e0e\u3068\u7570\u306a\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u200b<span class=\"\" data-state=\"closed\"><span class=\"text-token-text-secondary\"> (<\/span><a class=\"text-green-600 !no-underline\" href=\"https:\/\/www.zenbycat.org\/blog\/2021-treatment-with-oral-formulations-of-gs-441524\" target=\"_blank\" rel=\"noopener noreferrer\">Zen By Cat | House of Nekko | Home<\/a><span class=\"text-token-text-secondary\">)<\/span><\/span>\u200b\u3002<\/p>\n<h3>\u53c2\u8003\u6587\u732e<\/h3>\n<ul>\n<li><a target=\"_new\" rel=\"noreferrer noopener\">Cornell University College of Veterinary Medicine<\/a><\/li>\n<li><a href=\"https:\/\/www.zenbycat.org\/\" target=\"_new\" rel=\"noreferrer noopener\">ZenByCat<\/a><\/li>\n<li><a href=\"https:\/\/avmajournals.avma.org\/\" target=\"_new\" rel=\"noreferrer noopener\">Journal of the American Veterinary Medical Association<\/a><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"mt-1 flex gap-3 empty:hidden juice:-ml-3\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"w-full text-token-text-primary\" dir=\"auto\" data-testid=\"conversation-turn-8\" data-scroll-anchor=\"false\">\n<div class=\"py-2 juice:py-[18px] px-3 text-base md:px-4 m-auto md:px-5 lg:px-1 xl:px-5\">\n<div class=\"mx-auto flex flex-1 gap-3 text-base juice:gap-4 juice:md:gap-6 md:max-w-3xl lg:max-w-[40rem] xl:max-w-[48rem]\">\n<div class=\"group\/conversation-turn relative flex w-full min-w-0 flex-col\">\n<div class=\"flex-col gap-1 md:gap-3\">\n<div class=\"flex flex-grow flex-col max-w-full\">\n<div class=\"min-h-[20px] text-message flex flex-col items-start whitespace-pre-wrap break-words [.text-message+&amp;]:mt-5 juice:w-full juice:items-end overflow-x-auto gap-2\" dir=\"auto\" data-message-author-role=\"user\" data-message-id=\"aaa2a2b5-65b2-414c-b728-7100f465f854\">\n<div class=\"flex w-full flex-col gap-1 juice:empty:hidden items-end rtl:items-start\">\n<div class=\"relative max-w-[70%] rounded-3xl bg-[#f4f4f4] px-5 py-2.5 dark:bg-token-main-surface-secondary\">\n<div class=\"w-full text-token-text-primary\" dir=\"auto\" data-testid=\"conversation-turn-9\" data-scroll-anchor=\"false\">\n<div class=\"py-2 juice:py-[18px] px-3 text-base md:px-4 m-auto md:px-5 lg:px-1 xl:px-5\">\n<div class=\"mx-auto flex flex-1 gap-3 text-base juice:gap-4 juice:md:gap-6 md:max-w-3xl lg:max-w-[40rem] xl:max-w-[48rem]\">\n<div class=\"group\/conversation-turn relative flex w-full min-w-0 flex-col agent-turn\">\n<div class=\"flex-col gap-1 md:gap-3\">\n<div class=\"flex flex-grow flex-col max-w-full\">\n<div class=\"min-h-[20px] text-message flex flex-col items-start whitespace-pre-wrap break-words [.text-message+&amp;]:mt-5 juice:w-full juice:items-end overflow-x-auto gap-2\" dir=\"auto\" data-message-author-role=\"assistant\" data-message-id=\"ccd6aac0-8c56-40cb-8e71-1269bbceaa5e\">\n<div class=\"flex w-full flex-col gap-1 juice:empty:hidden juice:first:pt-[3px]\">\n<div class=\"markdown prose w-full break-words dark:prose-invert light\">\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"mt-1 flex gap-3 empty:hidden juice:-ml-3\">\n<div class=\"pr-2 lg:pr-0\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"w-full text-token-text-primary\" dir=\"auto\" data-testid=\"conversation-turn-10\" data-scroll-anchor=\"false\">\n<div class=\"py-2 juice:py-[18px] px-3 text-base md:px-4 m-auto md:px-5 lg:px-1 xl:px-5\">\n<div class=\"mx-auto flex flex-1 gap-3 text-base juice:gap-4 juice:md:gap-6 md:max-w-3xl lg:max-w-[40rem] xl:max-w-[48rem]\">\n<div class=\"group\/conversation-turn relative flex w-full min-w-0 flex-col\">\n<div class=\"flex-col gap-1 md:gap-3\">\n<div class=\"flex flex-grow flex-col max-w-full\">\n<div class=\"min-h-[20px] text-message flex flex-col items-start whitespace-pre-wrap break-words [.text-message+&amp;]:mt-5 juice:w-full juice:items-end overflow-x-auto gap-2\" dir=\"auto\" data-message-author-role=\"user\" data-message-id=\"aaa22e31-0e25-4830-9fbc-8281720f437a\">\n<div class=\"flex w-full flex-col gap-1 juice:empty:hidden items-end rtl:items-start\">\n<div class=\"relative max-w-[70%] rounded-3xl bg-[#f4f4f4] px-5 py-2.5 dark:bg-token-main-surface-secondary\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>GS-441524\u306e\u6cbb\u7642\u306b\u3064\u3044\u3066\u306e\u8ad6\u6587 GS-441524\u306f\u3001\u732b\u4f1d\u67d3\u6027\u8179\u819c\u708e\uff08FIP\uff09\u306b\u5bfe\u3059\u308b\u52b9\u679c\u7684\u306a\u6cbb\u7642\u6cd5\u3068\u3057\u3066\u5e83\u304f\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u7814\u7a76\u8ad6\u6587\u3082\u8907\u6570\u5b58\u5728\u3057\u3001\u305d\u306e\u6cbb\u7642\u52b9\u679c\u3084\u30e1\u30ab\u30cb\u30ba\u30e0\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u63a2\u6c42\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4ee5\u4e0b\u306f [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-2338","post","type-post","status-publish","format-standard","hentry","category-1"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.soyokazesogo.com\/blog\/wp-json\/wp\/v2\/posts\/2338","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.soyokazesogo.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.soyokazesogo.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.soyokazesogo.com\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.soyokazesogo.com\/blog\/wp-json\/wp\/v2\/comments?post=2338"}],"version-history":[{"count":1,"href":"https:\/\/www.soyokazesogo.com\/blog\/wp-json\/wp\/v2\/posts\/2338\/revisions"}],"predecessor-version":[{"id":2339,"href":"https:\/\/www.soyokazesogo.com\/blog\/wp-json\/wp\/v2\/posts\/2338\/revisions\/2339"}],"wp:attachment":[{"href":"https:\/\/www.soyokazesogo.com\/blog\/wp-json\/wp\/v2\/media?parent=2338"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.soyokazesogo.com\/blog\/wp-json\/wp\/v2\/categories?post=2338"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.soyokazesogo.com\/blog\/wp-json\/wp\/v2\/tags?post=2338"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}